CacSFMs: Citric Acid Cycle Binding Structural & Functional Motifs - v. β May 2016.
© University Dr Tahar Moulay, Saida.


Project realized by:Abdalla Salem and Mubarka Khatir (in their project of MSc in Biology, 2015-2016)

Proposed & supervised by: Dr. Abdelkrim Rachedi, e-mail: rachedi@bioinformaticstools.org

Reference: SALEM Abdellahi, RACHEDI Abdelkrim. STRUCTURAL/FUNCTIONAL MOTIFS IN THE ENZYMES OF THE KREBS CYCLE, 1ER SEMINAIRE DE BIOINFORMATIQUE, April 04-06, 2017, Blida, Algeria.

Citric Acid Cycle Binding Structural & Functional Motifs
- CacSFMs database-
Find CAC SFMs by Enzymes
CITRATE SYNTHASE   
ACONITASE   
ISOCITRATE DEHYDROGENASE   
ALPHA-KETOGLUTARATE DEHYDROGENASE   
SUCCINYL-COA-SYNTHETASE   
SUCCINIC SEMIALDEHYDE DEHYDROGENASE   
DELTA (1)-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE   
SUCCINATE DEHYDROGENASE   
SUCCINYLGLUTAMIC SEMIALDEHYDE DEHYDROGENASE   
FUMARASE   
MALATE DEHYDROGENASE TYPE 2   
   << Click on the list to find out ..
Find CAC SFMs by PDB entries
1AJ8   1IXE   2C6X   2P2W   2R9E   6CSC   1ACO   1FGH   1L5J   1ITW   1XKD   2UXR   4AJ3   4AJB   4BNP   3INM   4L06   4L04   4L03   4KZO   4AJR   4AJC   3O9Z   1CW4   2BWO   2BWN   2W8Q   4LH2   2DJL   3JU8   4APB   2DFD   
   << Click on the list to find out ..
Find CAC SFMs by Ligands
CIT   FLC   SDX   TRA   ATH   ICT   AKG   SCA   SIN   FUM   MLT   
   << Click on the list to find out ..
There are 5 SFM Motifs:
PDB EntryTitleDetermination MethodResolutionR-Factor
4L04alpha-Ketoglutarate dehydrogenaseX-RAY2.870.200
Motif No. / ChainModeBound Ligand
/(Nbr. in PDB)		Show Details
1 / A   > Structure: SSHSLLH
  > Sequence: TSNRRRDEA 		AKG
/(501)		 [+]
  > Graphics rep1: [+]
  > Graphics rep2: [+]
  > Graphics rep3: [+]
2 / B   > Structure: SSHLLH +1w
  > Sequence: TSNRRRDA 		AKG
/(501)		 [+]
  > Graphics rep1: [+]
  > Graphics rep2: [+]
  > Graphics rep3: [+]
3 / C   > Structure: SSHLH
  > Sequence: TSNRRRD 		AKG
/(501)		 [+]
  > Graphics rep1: [+]
  > Graphics rep2: [+]
  > Graphics rep3: [+]
4 / D   > Structure: SSHLH
  > Sequence: TNRRRD 		AKG
/(501)		 [+]
  > Graphics rep1: [+]
  > Graphics rep2: [+]
  > Graphics rep3: [+]
5 / E   > Structure: SSHLLH
  > Sequence: TSNRRRDA 		AKG
/(501)		 [+]
  > Graphics rep1: [+]
  > Graphics rep2: [+]
  > Graphics rep3: [+]